A high-grain diet causes massive disruption of ruminal epithelial tight junctions in goats

By Jun-hua Liu, Ting-ting Xu, Yu-jie Liu, Wei-yun Zhu, Sheng-yong Mao

Published on 01/08/2013

The ruminal epithelial barrier is a critical component of the immune system in ruminants. Breakdown of the ruminal epithelial barrier function is frequently observed in ruminants fed high-grain diets. This study in goats demonstrated a high-grain diet caused profound ruminal epithelial cellular damage and changes in tight junctions, which was associated with a local inflammatory response.


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